South of Market Vacations from $280

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your South of Market Vacation

Take all the hassle out of organizing your next escape by booking a South of Market vacation package. Take in the sights and sounds of this enticing neighborhood and enjoy all it has to offer. Some top nearby attractions to see during your trip to South of Market include Pier 39, Lombard Street and Palace of Fine Arts. Expedia is here to help put your plans into action. Book your dream South of Market vacation now.

The Latest South of Market Vacation Packages

Price found within the past 48 hours. Click for updated prices.
SF Central Hotel

SF Central Hotel

2 out of 5
South of Market
Save 100% on your flight
Price was $464, price is now $280 per person
$280
per person
Mar 11 - Mar 14
found 1 hour ago
Roundtrip flight included
Portland (PDX) to San Francisco (SFO)
6.2/10 (862 reviews)
No parking needed. The facility looked decent on the outside, but very dated and run down on the inside. It's a place to sleep for the night. The Becks motel/hotel in the Castro was a much better experience. Some older hotels just have that lived in look.

Reviewed on Oct 26, 2025

San Carlos Inn

San Carlos Inn

2 out of 5
Save 100% on your flight
Price was $737, price is now $363 per person
$363
per person
Feb 6 - Feb 9
found 10 hours ago
Roundtrip flight included
Carlsbad (CLD) to San Francisco (SFO)
7/10 Good! (316 reviews)
the inn is not a chain and is staff is always friendly . i support local business . I am happy for on site parking near rooms . Glad rooms are street level and no need for stairs/elevator . local motel in downtown dining shopping san carlos area . Am lucky dec 6 last minute reservation . I sheltered here , my job nearby .the inn is small , fits right in the downtown plan ? Bed and pillows above average for me .so is the mini fridge-microwave / heater-ac / cable ,too.

Reviewed on Dec 8, 2025

The Mosser

The Mosser

3 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $490, price is now $296 per person
$296
per person
Mar 4 - Mar 7
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
8/10 Very Good! (1,002 reviews)
there was a dirty bandaid on the floor and the carpet was dirty

Reviewed on Dec 16, 2025

Montage Healdsburg

Montage Healdsburg

5 out of 5
Save 100% on your flight
Price was $1,954, price is now $1,221 per person
$1,221
per person
Mar 13 - Mar 16
found 12 hours ago
Roundtrip flight included
San Diego (SAN) to San Francisco (SFO)
9.6/10 Exceptional! (113 reviews)
Clean room, kind and helpful staff. Nice ambiance in vineyard.

Reviewed on Nov 30, 2025

Alpine Inn And Suites

Alpine Inn And Suites

2 out of 5
Bayshore Heights
Save 100% on your flight
Price was $1,273, price is now $798 per person
$798
per person
Feb 6 - Feb 9
found 14 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
7.4/10 Good! (1,002 reviews)
Room was spotless. I got into town late. Booked with another hotel and their heater was broken. I booked with Alpine Inn and Suites and they were so anxious to accommodate me. I did not arrive till almost midnight and the front desk stayed up and waited for me! The last hotel was a total dive and upon arrival here I was so relieved and distressed. What a gem! Clean, courteous, and very helpful! Thank you so much!!

Reviewed on Dec 16, 2025

Where to stay in South of Market

Find the best South of Market areas and neighborhoods for the activities you enjoy most. Learn more about South of Market
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

South of Market Hotel Deals

Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown

3 out of 5
701 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $208 total per night from Jan 6 to Jan 7
$208 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,847 reviews)
The front desk staff were excellent.

Reviewed on Dec 13, 2025

Hyatt Place San Francisco Downtown
LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $230 total per night from Dec 19 to Dec 20
$230 total
Dec 19 - Dec 20
Total with taxes and fees
9.4/10 Exceptional! (2,369 reviews)
Love the concierge, very pleasant!

Reviewed on Dec 14, 2025

LUMA Hotel San Francisco
Soma House

Soma House

3.5 out of 5
121 7th Street San Francisco CA
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from Dec 21 to Dec 22
$125 total
Dec 21 - Dec 22
Total with taxes and fees
7.6/10 Good! (889 reviews)
Staff was super friendly and welcoming. Checking in and out was a breeze. Hotel and room was clean and comortable. Breakfast was surprisingly decent with low carb egg bite options and tea. For the price the area is great, within walking distance to union square and china town. BART access is convenient ...

Reviewed on Dec 7, 2025

Soma House
See all 4,910 properties in South of Market
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in South of Market

Moscone Convention Center

Moscone Convention Center

During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and notable monuments in this vibrant area.

Moscone Convention Center
Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
San Francisco Museum of Modern Art featuring a city

San Francisco Museum of Modern Art

Displaying artworks from Frida Kahlo to Andy Warhol, this museum of modern and contemporary art is one of the largest of its kind in the United States.

San Francisco Museum of Modern Art

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
Visit de Young Museum in Golden Gate Park

de Young Museum General Admission Ticket

$20
per adult
88% of travellers recommend
de Young Museum General Admission Ticket
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.